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(Rac)-OSMI-1
Biological Activity：(Rac)-OSMI-1 is the racemate of OSMI-1. OSMI-1 is a cell-permeable O-GlcNAc transferase (OGT) inhibitor with an IC50 value of 2.7 μM. OSMI-1 inhibits protein O-linked N-acetylglucosamine (O-GlcNAcylation) in several mammalian cell lines without qualitatively altering cell surface N- or O-linked glycans[2].
Research Area：Metabolic Disease
Targets：Acyltransferase
Related Screening Libraries:Bioactive Compound Library Plus;Metabolism/Protease Compound Library;Lipid Metabolism Compound Library ;Targeted Diversity Library;
Related Small Molecules:RP-64477;Enniatin A;IWP-12;ABT-046;PF-04620110;ACAT-IN-5;TP-020;Diacylglycerol acyltransferase inhibitor-1;JNJ-DGAT2-A;DGAT-1 inhibitor 2;Lateritin;OSMI-3;Avasimibe;Nevanimibe hydrochloride;FCE 28654;YM17E;RP 70676;ACAT-IN-3;Pactimibe;Pradigastat;CP-113818;VULM 1457;A 922500;ACAT-IN-6;AZD3988;T863;PF-06471553;ESI-05;Fumonisin B1
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