(R)-(-)-Gossypol

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(R)-(-)-Gossypol

CAS No. : 90141-22-3

Biological Activity:(R)-(-)-Gossypol (AT-101) is the levorotatory isomer of a natural product Gossypol. AT-101 is determined to bind to Bcl-2, Mcl-1 and Bcl-xL proteins with Kis of 260±30 nM, 170±10 nM, and 480±40 nM, respectively.

Research Area:Cancer

Targets:Autophagy|Bcl-2 Family

Related Small Molecules:BI-3812;Pyridoclax;PUMA BH3 TFA;Dehydrocorydaline;Bufarenogin;Murizatoclax;Obatoclax;CYD-2-11;BM 957;(S)-Gossypol (acetic acid);A-385358;Mcl-1 inhibitor 6;S55746;Anticancer agent 63;MCL-1/BCL-2-IN-2;Anticancer agent 65;(E)-Ferulic acid-d3;Bcl-2-IN-8;S65487 hydrochloride;PI-1840;MIK665;WEHI-539;Bax activator-1;UBX1325;Mcl-1 inhibitor 3;Maritoclax;ABT 737-d8

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