PROTAC BRD4 Degrader-10

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PROTAC BRD4 Degrader-10

CAS No. : 2417370-49-9

Biological Activity:PROTAC BRD4 Degrader-10 (compound 8b) is a PROTAC connected by ligands for von Hippel-Lindau and BRD4. PROTAC BRD4 Degrader-10 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 1.3 nM and 18 nM, respectively.

Research Area:Cancer

Targets:Epigenetic Reader Domain|ADC Cytotoxin|PROTACs

Related Small Molecules:Sandramycin;PROTAC Sirt2 Degrader-1;DB0614;RVX-297;BRD4 Inhibitor-19;UNC6349 (Ket2);PROTAC VEGFR-2 degrader-2;Curcumin;(R)-Camptothecin-d5;GSK6853;dTAGV-1-NEG;CCT367766 formic;GSK4028;SR-0813;Dolastatin 10;HDAC6 degrader-1;PROTAC Axl Degrader 2;Inobrodib;PhosTAC7;MS98;Apabetalone;INX-SM-56;OF-1;I-CBP112;JPS014;DC10SMe;PROTAC PARP1 degrader;A-485;MD-224

Trending products:Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  |  Fluorescent Dye  |  PROTAC  |  Isotope-Labeled Compounds  |  Oligonucleotides

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