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Polygalasaponin F
CAS No. : 882664-74-6
Biological Activity:Polygalasaponin F, an oleanane-type triterpenoid saponin extracted from Polygala japonica, decreases the release of the inflammatory cytokine tumor necrosis factor a (TNFa). Polygalasaponin F reduces neuroinflammatory cytokine secretion through the regulation of the TLR4-PI3K/AKT-NF-kB signaling pathway .
Research Area:Inflammation/Immunology
Targets:Akt|NF-κB|Toll-like Receptor (TLR)|PI3K
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