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Pentamidine isethionate
CAS No. : 140-64-7
Biological Activity：Pentamidine isethionate (MP-601205 isethionate) is an antimicrobial agent and interferes with DNA biosynthetics. Pentamidine isethionate inhibits parasite Leishmania infantum with an IC50 of 2.5 μM. Pentamidine isethionate is a potent and selective protein tyrosine phosphatases (PTPases) and phosphatase of regenerating liver (PRL) inhibitor. Pentamidine isethionate has the potential for Gambian trypanosomiasis, antimony-resistant leishmaniasis, and Pneumocystis carinii pneumonia treatment. Antitumor and antibacterial activities[2][3][4].
Research Area：Infection|Cancer
Targets：Parasite|Fungal|Bacterial|Antibiotic|Phosphatase
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Related Small Molecules:Antifungal agent 20;(+)-Isopulegol;Sandramycin;LLO (91-99);Gepotidacin;Oritavancin;Monascorubrin;SR9186;Antileishmanial agent-2;Azlocillin sodium salt;Herbimycin A;Antibacterial agent 45;Debneyol;Leucomycin;Isouvaretin;Haloprogin;GNF362;Antibacterial agent 99;Vidarabine monohydrate;Nafcillin;Antitubercular agent-28
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