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Pemetrexed
CAS No. : 137281-23-3
Biological Activity:Pemetrexed (LY231514) is an antifolate, the Ki values of the pentaglutamate of Pemetrexed (LY231514) are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively.
Research Area:Cancer
Targets:Autophagy|Antifolate
Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;FDA-Approved Drug Library;Anti-Cancer Compound Library;Autophagy Compound Library;Peptidomimetic Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Anti-COVID-19 Compound Library;Orally Active Compound Library;FDA Approved & Pharmacopeial Drug Library;Drug-Induced Liver Injury (DILI) Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Targeted Diversity Library;Chemotherapy Drug Library;EMA-Approved Drug Library;FDA-Approved Anticancer Drug Library;Human Metabolite Library;Anti-Prostate Cancer Compound Library;
Related Small Molecules:Cycloguanil D6 Nitrate;FRα-IN-1;Edatrexate;Aminopterin;TNP-351;Metoprine;LY309887;Tetroxoprim;LY 222306;Levomefolate calcium;Lometrexol hydrate;Trimetrexate trihydrochloride;Mirvetuximab;DHFR-IN-3;Folinic acid disodium;EC0489;Folinic acid calcium;DHFR-IN-2;EC0488;Levomefolate-13C5 calcium;Pelitrexol;LSN 3213128;Fanotaprim;Aditoprime;Trimetrexate glucuronate;Diaveridine
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