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Palmatine hydroxide
CAS No. : 131-04-4
Biological Activity：Palmatine hydroxide is an orally active and irreversible indoleamine 2,3-dioxygenase 1 (IDO-1) inhibitor with IC50s of 3 μM and 157μM against HEK 293-hIDO-1 and rhIDO-1, respectively. Palmatine hydroxide can also inhibit West Nile virus (WNV) NS2B-NS3 protease in an uncompetitive manner with an IC50 of 96 μM. Palmatine hydroxide shows anti-cancer, anti-oxidation, anti-inflammatory, neuroprotection, antibacterial, anti-viral activities[2][3][4][5].
Research Area：Cancer|Infection|Metabolic Disease|Inflammation/Immunology|Neurological Disease
Targets：Parasite|Indoleamine 2,3-Dioxygenase (IDO)|Bacterial|Aurora Kinase|Apoptosis|Virus Protease
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