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NE-100 hydrochloride
CAS No. : 149409-57-4
Biological Activity:NE-100 (hydrochloride) is a potent and selective sigma-1 receptor antagonist with an IC50 of 4.16 nM. NE-100 (hydrochloride) exerts antipsychotic activity in vivo[1]. NE-100 (hydrochloride) also suppresses ER stress-induced hippocampal cell death[2].
Research Area:Neurological Disease
Targets:Sigma Receptor
Related Screening Libraries:Bioactive Compound Library Plus;Neuronal Signaling Compound Library;Endoplasmic Reticulum Stress Compound Library;Human Metabolite Library;
Related Small Molecules:BD1063 dhydrochloride;Phenyltoloxamine;E1R;EST73502;(±)-Vesamicol hydrochloride;Sigma-LIGAND-1;BMY-14802 hydrochloride;SKF 83959 hydrobromide;Pentoxyverine;SR-31747 free base;Antidepressant agent 3;PD 144418;EST64454 hydrochloride;Glycerol phenylbutyrate-d5;Rimcazole dihydrochloride;Siramesine hydrochloride;Antidepressant agent 4;OPC-14523 hydrochloride;Blarcamesine;DuP 734;Panamesine
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