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MTI-31
CAS No. : 1567915-38-1
Biological Activity：MTI-31 is a potent, orally active and highly selective inhibitor of mTORC1 and mTORC2. MTI-31 is selective for mTOR (Kd: 0.20 nM) versus PIK3CA, PIK3CB and PIK3G with >5,000 fold selectivity in mTOR binding assays. MTI-31 shows an IC50 of 39 nM for mTOR in LANCE assay of mTOR substrate phosphorylation with 100 μM ATP. MTI-31 can be used for the research of breast cancer.
Research Area：Cancer|Inflammation/Immunology
Targets：mTOR
Related Screening Libraries:Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Kinase Inhibitor Library;PI3K/Akt/mTOR Compound Library;Stem Cell Signaling Compound Library;Anti-Cancer Compound Library;Autophagy Compound Library;Anti-Aging Compound Library;Antioxidant Compound Library;Differentiation Inducing Compound Library;Reprogramming Compound Library;Oxygen Sensing Compound Library;Glycolysis Compound Library;Cytoskeleton Compound Library;Orally Active Compound Library;Glutamine Metabolism Compound Library;Anti-Breast Cancer Compound Library;Anti-Lung Cancer Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Blood Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Anti-Obesity Compound Library;Angiogenesis-Related Compound Library;Lipid Metabolism Compound Library ;Glucose Metabolism Compound Library;Anti-Liver Cancer Compound Library ;Anti-Colorectal Cancer Compound Library ;Anti-Prostate Cancer Compound Library;Anti-Pulmonary Fibrosis Compound Library;Cancer Stem Cells Compound Library;
Related Small Molecules:D-α-Hydroxyglutaric acid disodium;Cyclovirobuxine D;WYE-354;L-Leucine-1-13C,15N;PI-103-d8;Palomid 529;PI-103 Hydrochloride;RMC-5552;OXA-01;L-Leucine-15N;PI3K/mTOR Inhibitor-6;PI3K/mTOR Inhibitor-1;HDACs/mTOR Inhibitor 1;Chromeceptin;hSMG-1 inhibitor 11e;PI3Kα/mTOR-IN-1;RapaLink-1;Torin 1;Dihydromyricetin;PI3K/mTOR Inhibitor-4;L-Leucine-13C6,15N;PI3K/mTOR Inhibitor-7;VS-5584;Dihydroevocarpine;Torin 2;Polyphyllin I;MHY1485
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