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MPT0G211
CAS No. : 2151853-97-1
Biological Activity：MPT0G211 is a potent, orally active and selective HDAC6 inhibitor (IC50=0.291 nM). MPT0G211 displays >1000-fold selective for HDAC6 over other HDAC isoforms. MPT0G211 can penetrate the blood-brain barrier. MPT0G211 ameliorates tau phosphorylation and cognitive deficits in an Alzheimer’s disease model. MPT0G211 has anti-metastatic and neuroprotective effects. Anticancer activities[2][3].
Research Area：Cancer|Neurological Disease
Targets：HDAC
Related Screening Libraries:Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;Epigenetics Compound Library;Histone Modification Research Compound Library;Anti-Cancer Compound Library;Anti-Aging Compound Library;Reprogramming Compound Library;Oxygen Sensing Compound Library;Orally Active Compound Library;Anti-Alzheimer’s Disease Compound Library;Neuroprotective Compound Library;Anti-Breast Cancer Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Blood Cancer Compound Library;Neurodegenerative Disease-related Compound Library;Anti-Liver Cancer Compound Library ;Osteogenesis Compound Library;
Related Small Molecules:Pivanex;Crotonoside;MPT0B390;RSC133;HDAC1/6-IN-1;HDAC/HSP90-IN-4;JPS014;HDAC-IN-4;HDAC-IN-27;1-Alaninechlamydocin;SKLB-23bb;Tacedinaline;HPOB;HDAC-IN-28;CG347B;Tubacin;HDAC10-IN-1;HDAC6-IN-6;Resminostat;Alteminostat;HDAC-IN-47;Ivaltinostat formic;Crebinostat;FNDR-20123 free base;UF010;Homobutein;Ac-Lys-AMC;HDACs/mTOR Inhibitor 1;BRD73954
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