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MID-1
CAS No. : 312608-54-1
Biological Activity：MID-1 is a disruptor of MG53-IRS-1 (Mitsugumin 53-insulin receptor substrate-1) interaction. MID-1 disrupts molecular association of MG53 with IRS-1 and abolishes MG53-induced IRS-1 ubiquitination and degradation in skeletal muscle, leading to elevated IRS-1 expression level and increased insulin signaling and glucose uptake.
Research Area：Metabolic Disease
Targets：Insulin Receptor
Related Screening Libraries:Bioactive Compound Library Plus;Kinase Inhibitor Library;Protein Tyrosine Kinase Compound Library;Anti-Aging Compound Library;Targeted Diversity Library;
Related Small Molecules:AGL-2263;KU14R;SU4984;HNMPA-(AM)3;S961 TFA;OI338;Gastric Inhibitory Peptide, porcine;MSDC 0160;[Tyr0] Gastric Inhibitory Peptide (23-42), human;AVJ16;GIP, human;GSK1838705A;DA-JC4;MSDC-0602K;AG1024;(Pro3) GIP, human;HNMPA;BMS-754807;GSK1904529A;NVP-ADW742;Linsitinib-d3;GIP (1-30) amide,human acetate
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