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Melagatran
CAS No. : 159776-70-2
Biological Activity:Melagatran is a direct and orally active inhibitor of thrombin, without interacting with any other enzymes in the coagulation cascade or fibrinolytic enzymes aside from thrombin. Melagatran does not require endogenous co-factors for its antithrombin effect and may help to alleviate some of the damaging effects of endotoxemia. Melagatran has the potential to provide a rational approach in the prevention of arterial occlusion[2].
Research Area:Cardiovascular Disease
Targets:Thrombin
Related Small Molecules:OM-189;Thrombin Inhibitor 2;Razaxaban hydrochloride;Desethyl KBT-3022;Idraparinux sodium;TP508;Inogatran;RWJ-445167;Napsagatran hydrate;BAY 1217224;Thrombin (MW 37kDa);Ximelagatran-d11;(1R,3S)-THCCA-Asn;Sfllrnpndkyepf
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