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Levobupivacaine hydrochloride
CAS No. : 27262-48-2
Biological Activity：Levobupivacaine hydrochloride ((S)-(-)-Bupivacaine monohydrochloride) is a long-acting amide local anaesthetic. Levobupivacaine hydrochloride exerts anaesthetic and analgesic effects through reversible blockade of neuronal sodium channel. Levobupivacaine hydrochloride can inhibit impulse transmission and conduction in cardiovascular and other tissues, possessing certain cardiac and CNS toxicity. Levobupivacaine hydrochloride is metabolized by hepatic cytochrome P450 (CYP450) enzymes in vivo. Levobupivacaine hydrochloride can also induce ferroptosis by miR-489-3p/SLC7A11 signaling in gastric cancer[2][3].
Research Area：Neurological Disease|Cancer
Targets：Ferroptosis|Sodium Channel
Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Apoptosis Compound Library;Membrane Transporter/Ion Channel Compound Library;FDA-Approved Drug Library;Anti-Cancer Compound Library;CNS-Penetrant Compound Library;Drug Repurposing Compound Library;Ferroptosis Compound Library;NMPA-Approved Drug Library;FDA Approved & Pharmacopeial Drug Library;Neuroprotective Compound Library;Rare Diseases Drug Library;Children’s Drug Library;Protein-protein Interaction Inhibitor Library;Sodium Channel Blocker Library;FDA-Approved Anticancer Drug Library;Human Metabolite Library;Anti-Prostate Cancer Compound Library;Non-steroidal Anti-Inflammatory Compound Library;
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