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Leptomycin A
CAS No. : 87081-36-5
Biological Activity：Leptomycin A, a Streptomyces metabolite, is an inhibitor of CRM1 (exportin 1) that blocks CRM1 interaction with nuclear export signals, preventing the nuclear export of a broad range of proteins. Leptomycin A suppresses HIV-1 replication. Less potent than Leptomycin B[2].
Research Area：Infection
Targets：HIV|Antibiotic|CRM1
Related Small Molecules:Sandramycin;Oritavancin;Monascorubrin;Azlocillin sodium salt;Herbimycin A;Leucomycin;HIV-1 TAT (48-60);Vidarabine monohydrate;Nafcillin;Seletracetam lithium;Staurosporine;HIV-IN-2;Clotrimazole-d5;SQ109;(R)-Camptothecin-d5;Neomycin sulfate;Triptonine B;Framycetin;Colistin sulfate;Pyrantel;FC131
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