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KU-57788
CAS No. : 503468-95-9
Biological Activity：KU-57788 (NU7441) is a highly potent and selective DNA-PK inhibitor with an IC50 of 14 nM. KU-57788 is an NHEJ pathway inhibitor. KU-57788 also inhibits PI3K and mTOR with IC50s of 5.0 and 1.7 μM, respectively.
Research Area：Cancer
Targets：CRISPR/Cas9|DNA-PK
Related Screening Libraries:Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;Kinase Inhibitor Library;PI3K/Akt/mTOR Compound Library;Anti-Cancer Compound Library;Anti-Aging Compound Library;Oxygen Sensing Compound Library;Glycolysis Compound Library;Cytoskeleton Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Anti-Obesity Compound Library;Glucose Metabolism Compound Library;Targeted Diversity Library;Cancer Stem Cells Compound Library;
Related Small Molecules:PI-103-d8;PI-103 Hydrochloride;SF2523;Mca-VDQVDGW-Lys(Dnp)-NH2;Cas9-IN-1;Cas9-IN-2;BAY-8400;DNA-PK-IN-6;Torin 2;NU 7026;PIK-90;PIK-75;(R)-VX-984;LY294002 hydrochloride;CC-115;DNA-PK-IN-4;AMA-37;DNA-PK-IN-7;DNA-PK-IN-9;NU5455;Samotolisib;DNA-PK-IN-1;VX-984;ATR-IN-15
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