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Keap1-Nrf2-IN-8
CAS No. : 2769963-54-2
Biological Activity：Keap1-Nrf2-IN-8 (compound 12d) is a potent Keap1-Nrf2 PPI (Keap1-Nrf2 protein−protein interaction) inhibitor with IC50s of 64.5 nM and 14.2 nM for FP and TR-FRET assays, respectively. Keap1-Nrf2-IN-8 significantly increases the mRNA levels of Nrf2 downstream genes, GSTM3, HMOX2 and NQO1.
Research Area：Inflammation/Immunology
Targets：Keap1-Nrf2
Related Small Molecules:Mangiferin;Antioxidant agent-5;Curcumin;Antroquinonol;Resveratrol;NXPZ-2;Eriodictyol;ML334;S-Allylmercaptocysteine;NK-252;Ginsenoside Rh3;4-Hydroxyphenylacetic acid-d6;Kinsenoside;Pyridoxine-d3 hydrochloride;Pyridoxine;Carnosol;Corynoline;5,7-Dihydroxychromone;Carlinoside;Pyridoxine-d2 hydrochloride;Pyridoxine-13C4 hydrochloride;4-Hydroxyphenylacetic acid;Poricoic acid A;Hinokitiol;Nrf2-ARE/hMAO-B/QR2 modulator 1;CBR-470-2;Danshensu
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