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JNc-440

CAS No. : 1119503-63-7

Biological Activity：JNc-440 is a potent antihypertensive agent. JNc-440 can enhance the interaction of TRPV4 and Ca²⁺-activated potassium channel 3 (KCa2.3) in endothelial cells. JNc-440 can also enhance vasodilation, and exerted antihypertensive effects in mice.

Research Area：Cardiovascular Disease

Targets：TRP Channel|Potassium Channel

Related Screening Libraries:Bioactive Compound Library Plus;Membrane Transporter/Ion Channel Compound Library;Neuronal Signaling Compound Library;Anti-Cardiovascular Disease Compound Library;Mechanoreceptors Compound Library;

Related Small Molecules:V116517;GSK2332255B;Pregnenolone monosulfate sodium;Kv3 modulator 2;TRPC5-IN-4;OptoBI-1;Brompheniramine-d6 maleate;Pinacidil;SB-705498;AMP-PNP tetralithium;IK1 inhibitor PA-6;TRPC3/6-IN-1;ABT-239;Pyr3;VU590;Domiphen bromide;Asivatrep;Mesoridazine benzenesulfonate;Tetrandrine;20(S)-Ginsenoside Rg3;(S)-(+)-Modafinic acid-d5;Ononetin;TRPM8 antagonist 3;FEMA 4809;Ketanserin;Hydroxy-α-sanshool

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