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IRE1α kinase-IN-2
CAS No. : 1414938-21-8
Biological Activity：IRE1α kinase-IN-2 is a potent IRE1α kinase inhibitor, with an EC50 of 0.82 μM. IRE1α kinase-IN-2 inhibits IRE1α kinase autophosphorylation (IC50=3.12 μM). IRE1α kinase-IN-2 inhibits XBP1 mRNA splicing in the WT cell lines.
Research Area：Cancer
Targets：IRE1
Related Screening Libraries:Covalent Screening Library Plus;Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;Kinase Inhibitor Library;Anti-Cancer Compound Library;Anti-Aging Compound Library;Covalent Screening Library;Endoplasmic Reticulum Stress Compound Library;
Related Small Molecules:MKC8866;IXA4;4μ8C;GSK2850163 hydrochloride;B I09;IRE1α kinase-IN-3;IXA6;GSK2850163 (S enantiomer);IRE1α kinase-IN-5;KIRA6;MKC3946;3,6-DMAD dihydrochloride;Kira8;PAIR2;Toyocamycin;IRE1α kinase-IN-4;KIRA-7;KIRA9;STF-083010;IRE1α kinase-IN-1;MKC9989
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