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IRAK4-IN-15
CAS No. : 2667681-85-6
Biological Activity：IRAK4-IN-15 (compound 35) is a potent and selective IRAK4 inhibitor with an IC50 of 0.002 µM. IRAK4-IN-15 shows good human PK predictions with low intrinsic clearance. IRAK4-IN-15 shows great synergistic in vitro activity against MyD88/CD79 double mutant ABC-DLBCL in combination with Acalabrutinib. .
Research Area：Cancer
Targets：IRAK
Related Small Molecules:IRAK4-IN-8;Edecesertib;IRAK4-IN-22;IRAK inhibitor 2;PROTAC IRAK4 degrader-3;IRAK inhibitor 6;GNE-2256;IRAK4-IN-14;PROTAC IRAK4 degrader-1;HG-12-6;JH-X-119-01;IRAK4-IN-19;IRAK4-IN-6;KTX-582;IRAK4-IN-11;HS271;IRAK-4 protein kinase inhibitor 2;PROTAC IRAK4 degrader-6;IRAK4-IN-17;Ginsenoside Rb1;Zabedosertib;IRAK4-IN-12;IRAK-1-4 Inhibitor I;IRAK inhibitor 3;PROTAC IRAK4 degrader-7;KTX-955;Zimlovisertib;KTX-497
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