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INCB3344

CAS No. : 1262238-11-8

Biological Activity：INCB3344 is a potent, selective and orally bioavailable CCR2 antagonist with IC₅₀ values of 5.1 nM (hCCR2) and 9.5 nM (mCCR2) in binding antagonism and 3.8 nM (hCCR2) and 7.8 nM (mCCR2) in antagonism of chemotaxis activity.

Research Area：Inflammation/Immunology|Endocrinology

Targets：CCR

Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Immunology/Inflammation Compound Library;Small Molecule Immuno-Oncology Compound Library;Endocrinology Compound Library;Orally Active Compound Library;Anti-Liver Cancer Compound Library ;Anti-Pulmonary Fibrosis Compound Library;Chemokine Compound Library;

Related Small Molecules:LMD-009;PF-04634817 succinate;Vercirnon;CKLF1-C27;Bindarit;CCR6 antagonist 1;CCR6 inhibitor 1;CCR4-351 hydrochloride;BI 639667;ML604086;CCR4 antagonist 3-1;AZD2423;AZD2098;AZD-1678;R243;RS102895 hydrochloride;Vicriviroc maleate;BMS-639623;AZD-4818;INCB 3284 dimesylate;Maceneolignan H;CKLF1-C27 TFA;CCR3 antagonist 1;C-021;RPT193

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