Hypothemycin

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Hypothemycin

CAS No. : 76958-67-3

Biological Activity:Hypothemycin, a fungal polyketide, is a multikinase inhibitor with Kis of 10/70 nM, 17/38 nM, 90 nM, 900 nM/1.5 μM, and 8.4/2.4 μM for VEGFR2/VEGFR1, MEK1/MEK2, FLT-3, PDGFRβ/PDGFRα, and ERK1/ERK2, respectively[2].

Research Area:Cancer

Targets:MEK|FLT3|VEGFR|PDGFR|ERK

Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus;Macrocyclic Compound Library;

Related Small Molecules:(Z)-FeCP-oxindole;Avutometinib;VEGFR-2-IN-24;BMS-690514;AT9283;PROTAC VEGFR-2 degrader-2;(E/Z)-Zotiraciclib;Henatinib;Crotonoside;Cobimetinib racemate;PI3K/VEGFR2-IN-1;Flumatinib mesylate;IHMT-TRK-284;FLT3-IN-13;PDGFRα/FLT3-ITD-IN-2;FLT3/CDK4-IN-1;Corynoxeine;EBI-1051;PP58;Hydroxytanshinone IIA;Chiauranib;Foretinib;ZM323881 hydrochloride

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