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Helenalin
CAS No. : 6754-13-8
Biological Activity:Helenalin is an anti-inflammatory sesquiterpene lactone. Helenalin selectively inhibits transcription factor NF-κB by directly targeting p65. Helenalin has alkylating activity, targets the cysteine sulfhydryl groups in the p65 subunit of NF-κB, thereby inhibits its DNA binding[2].
Research Area:Cancer|Inflammation/Immunology
Targets:NF-κB
Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus;
Related Small Molecules:Akt/NF-κB/JNK-IN-1;Icariside F2;IKKγ NBD Inhibitory Peptide TFA;Mangiferin;Antioxidant agent-5;ALPK1-IN-1;Regaloside A;IMD-ferulic;SN52;5-Aminosalicylic Acid-D3 hydrochloride;Ginsenoside Rg1;Echinulin;Licochalcone D;QNZ;BIZ 114;NF-κΒ activator 1;Berbamine;NF-κΒ activator 2;20(S)-Ginsenoside Rg3;Ginsenoside Rd;Morusin;(R)-(-)-Ibuprofen;Ro 106-9920;Armepavine;Laquinimod;S-Allylmercaptocysteine
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