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HDAC/HSP90-IN-3
CAS No. : 2700035-54-5
Biological Activity：HDAC/HSP90-IN-3 (compound J5) is a potent and selective fungal Hsp90 and HDAC dual inhibitor, with IC50 values of 0.83 and 0.91 μM, respectively. HDAC/HSP90-IN-3 shows antifungal activity against azole resistant C. albicans. HDAC/HSP90-IN-3 can suppress important virulence factors and down-regulate drug-resistant genes ERG11 and CDR1.
Research Area：Infection
Targets：Fungal|HDAC|HSP
Related Small Molecules:Antifungal agent 20;Debneyol;Haloprogin;Staurosporine;Ciclopirox-d11;Ciclopirox olamine;Clotrimazole-d5;6BrCaQ;(R)-Camptothecin-d5;Ticlatone;Aminothiazole;Magnesium silicate;Pivanex;α-Terpinene;Hydroxyphenyllactic acid;Iprobenfos;116-9e;Crotonoside;Chlorphenesin;MPT0B390;Moniliformin sodium salt;HLF1-11;β-Amyrin acetate;Bifonazole;RSC133;Aszonapyrone A
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