For research use only. We do not sell to patients.
Hcyb1
Biological Activity：Hcyb1 is a highly selective, orally active PDE2 inhibitor. Hcyb1 has a highly selective inhibition of PDE2A (IC50=0.57 μM) and over 250-fold selectivity against other recombinant PDE family members. Hcyb1 produces neuroprotective and antidepressant‐like effects most likely mediated by cAMP/cGMP-CREB-BDNF signaling.
Research Area：Neurological Disease
Targets：Phosphodiesterase (PDE)
Related Screening Libraries:Bioactive Compound Library Plus;Metabolism/Protease Compound Library;Orally Active Compound Library;Anti-Alzheimer’s Disease Compound Library;Neuroprotective Compound Library;Neurodegenerative Disease-related Compound Library;Anti-Obesity Compound Library;Transcription Factor-Targeted Library;Anti-Colorectal Cancer Compound Library ;Antidepressant Compound Library;Anti-Prostate Cancer Compound Library;
Related Small Molecules:Senazodan hydrochloride;(E/Z)-HA155;Enpp/Carbonic anhydrase-IN-1;ATX inhibitor 22;Carbazeran citrate;Bay 60-7550;BC11-38;Deltarasin hydrochloride;Glaucine;Ziritaxestat;Udenafil-d7;D159687;ITI-214;PDE10-IN-5;ICI 153110;Furamidine dihydrochloride;ML-030;PDE4-IN-10;Mirodenafil-d7 dihydrochloride;PDE1-IN-4;PDE4B-IN-3;Cirsimarin;PF-03049423;IBMX;Pimobendan;Gisadenafil besylate;S32826 disodium
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Structurally and synthetically diverse biologically active compounds；
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