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Glembatumumab
CAS No. : 1020264-78-1
Biological Activity:Glembatumumab is a fully human IgG2 monoclonal antibody directed against the extracellular structural domain of GPNMB expressed in human breast cancer and melanoma. Glembatumumab can be coupled to the microtubule inhibitor monomethyl auristatin E to form glembatumumab vedotin. Glembatumumab vedotin is an antibody-drug coupling (ADC) with antitumor activity.
Research Area:Cancer
Targets:ADC Antibody
Related Small Molecules:Ozuriftamab;Upifitamab
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