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Gemfibrozil
CAS No. : 25812-30-0
Biological Activity：Gemfibrozil is an activator of PPAR-α, used as a lipid-lowering drug; Gemfibrozil is also a nonselective inhibitor of several P450 isoforms, with Ki values for CYP2C9, 2C19, 2C8, and 1A2 of 5.8, 24, 69, and 82 μM, respectively.
Research Area：Metabolic Disease|Cardiovascular Disease|Cancer
Targets：PPAR|Cytochrome P450
Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;Metabolism/Protease Compound Library;FDA-Approved Drug Library;Anti-Cancer Compound Library;Antiviral Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Antioxidant Compound Library;Anti-diabetic Compound Library;Oxygen Sensing Compound Library;Anti-Cardiovascular Disease Compound Library;NMPA-Approved Drug Library;Orally Active Compound Library;FDA Approved & Pharmacopeial Drug Library;Drug-Induced Liver Injury (DILI) Compound Library;Transcription Factor-Targeted Library;Lipid Metabolism Compound Library ;Tumorigenesis-Related Compound Library;Rare Diseases Drug Library;Antidepressant Compound Library;FDA-Approved Anticancer Drug Library;Human Metabolite Library;Nuclear Receptor Compound Library;
Related Small Molecules:SR9186;AMG-208;CYP1B1-IN-1;CYP2C9/CYP2C19-IN-1;Falcarindiol;Hypericin;5-Aminosalicylic Acid-D3 hydrochloride;Retinoic acid;PPARγ agonist 7;Galeterone;Ranitidine;Licarin B;Bergapten;Mifobate;Ginsenoside Rd;AS1810722;Isoglycycoumarin;Polygalaxanthone III;Phenyltoloxamine;Ezutromid;Seviteronel;β-Apo-8′-carotenal;Diosmetin-d3
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