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Gap19 TFA
Biological Activity：Gap19 TFA, a peptide derived from nine amino acids of the Cx43 cytoplasmic loop (CL), is a potent and selective connexin 43 (Cx43) hemichannel blocker. Gap19 TFA inhibits hemichannels caused by preventing intramolecular interactions of the C-terminus (CT) with the CL. Gap19 TFA is not blocking GJ channels or Cx40/pannexin-1 hemichannels. Gap19 TFA has protective effects against myocardial[2].
Research Area：Cardiovascular Disease
Targets：Gap Junction Protein
Related Screening Libraries:Bioactive Compound Library Plus;Anti-Cardiovascular Disease Compound Library;Cytoskeleton Compound Library;Peptide Library;
Related Small Molecules:AT-1002 TFA;Meclofenamic acid sodium hydrate;Gap 26;Carbenoxolone disodium;Meclofenamic acid-13C6;Larazotide acetate;Meclofenamic acid-d4;Danegaptide Hydrochloride;Rotigaptide;Gap19;TAT-Gap19 TFA;Tonabersat;Peptide5;Gap 27;Meclofenamic acid sodium
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