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Forskolin
CAS No. : 66575-29-9
Biological Activity：Forskolin (Coleonol) is a potent adenylate cyclase activator with an IC50 of 41 nM and an EC50 of 0.5 μM for type I adenylyl cyclase. Forskolin is also an inducer of intracellular cAMP formation[2]. Forskolin induces differentiation of various cell types and activates pregnane X receptor (PXR) and FXR[3]. Forskolin exerts a inotropic effect on the heart, and has platelet antiaggregatory and antihypertensive actions. Forskolin also induces autophagy[4][5].
Research Area：Cancer|Endocrinology|Metabolic Disease|Inflammation/Immunology
Targets：Adenylate Cyclase|Autophagy|FXR
Related Screening Libraries:Covalent Screening Library Plus;Natural Product Library Plus;Bioactive Compound Library Plus;GPCR/G Protein Compound Library; Immunology/Inflammation Compound Library;Metabolism/Protease Compound Library;Natural Product Library;Anti-Cancer Compound Library;Autophagy Compound Library;Covalent Screening Library;Reprogramming Compound Library;Anti-diabetic Compound Library;Lipid Compound Library;Endocrinology Compound Library;Terpenoids Library;Exosomes Compound Library;Targeted Diversity Library;Anti-Cancer Natural Product Library;Plant-Sourced Natural Product Library;Nuclear Receptor Compound Library;Coagulation and Anti-coagulation Compound Library;
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