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Fazirsiran
CAS No. : 2175009-08-0
Biological Activity：Fazirsiran (ARO-AAT) is a second-generation RNAi drug. Fazirsiran consistes of a cholesterol-conjugated RNAi trigger (chol-RNAi) to selectively degrade AAT mRNA by RNAi and a melittin-derived peptide conjugated to N-acetylgalactosamine (NAG) formulated as the excipient EX1 to promote endosomal escape of the chol-RNAi in hepatocytes.
Research Area：Metabolic Disease
Targets：Small Interfering RNA (siRNA)
Related Small Molecules:SLN124;Cemdisiran;Givosiran;Manusiran;Revusiran;AB-729;Teprasiran;Fitusiran;Patisiran sodium;Inclisiran;Tivanisiran;Lumasiran;Elebsiran;Lumasiran sodium;Zerlasiran;Vutrisiran
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
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