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Elubrixin tosylate
CAS No. : 960495-43-6
Biological Activity：Elubrixin tosylate (SB-656933 tosylate) is a potent, selective, competitive, reversible and orally active CXCR2 antagonist and an IL-8 receptor antagonist. Elubrixin tosylate inhibits neutrophil CD11b upregulation (IC50 of 260.7 nM) and shape change (IC50 of 310.5 nM). Elubrixin tosylate has the potential for inflammatory diseases research, such as inflammatory bowel disease and airway inflammation[2][3].
Research Area：Inflammation/Immunology
Targets：CXCR|Interleukin Related
Related Screening Libraries:Covalent Screening Library Plus;Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Immunology/Inflammation Compound Library;Clinical Compound Library;Small Molecule Immuno-Oncology Compound Library;Drug Repurposing Compound Library;Covalent Screening Library;Orally Active Compound Library;Angiogenesis-Related Compound Library;Targeted Diversity Library;Human Metabolite Library;Chemokine Compound Library;
Related Small Molecules:Nicotinamide N-oxide;AX-024;Ginsenoside F3;Perakizumab;FC131;PNRI-299;CXCR4 antagonist 2;AMG 487 (S-enantiomer);CTX-471;Ac-YVAD-CHO;CXCR4 antagonist 6;Deucravacitinib;CXCR2 antagonist 4;VUF11207 fumarate;Mulberroside A;NFAT Transcription Factor Regulator-1;IL-17A antagonist 1;Kansuinine B;Ginsenoside Rc;KRH-3955 hydrochloride;5(S)15(S)-DiHETE;IL-17A inhibitor 2;Anti-Mouse IL-1b Antibody;IT1t dihydrochloride;Raleukin;Ossirene;VGX-1027;RCGD423;Clazakizumab
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