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Elabela(19-32) TFA
Biological Activity：Elabela(19-32) TFA is an active fragment of ELABELA (ELA) that binds to apelin receptor (APJ). Elabela(19-32) TFA activates the Gαi1 and β-arrestin-2 signaling pathways with EC50s of 8.6 nM and 166 nM. Elabela(19-32) TFA induces receptor internalization and reduces arterial pressure, exerts positive inotropic effects on the heart.
Research Area：Cardiovascular Disease
Targets：Apelin Receptor (APJ)
Related Screening Libraries:Bioactive Compound Library Plus;Peptide Library;
Related Small Molecules:ML221;Apelin-13 TFA;ML233;[Pyr1]-Apelin-13;APJ receptor agonist 5;APJ receptor agonist 1;ELA-11(human) TFA;NH2-c[X-R-L-S-X]-K-G-P-(D-2Nal);AM-8123;MM 07;APJ receptor agonist 4;ELA-32(human) TFA;Azelaprag;ELA-21 (human);APJ receptor agonist 6;MM 54;CMF019;NH2-c[X-R-L-S-X]-K-G-P-(D-1Nal);Apelin agonist 1;APJ receptor agonist 3
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