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DK419
CAS No. : 2102672-22-8
Biological Activity：DK419 is a potent and orally active Wnt/β-catenin signaling inhibitor, with an IC50 of 0.19 μM. DK419 reduces protein lelvels of Axin2, β-catenin, c-Myc, Cyclin D1 and Survivin and induces production of pAMPK.
Research Area：Cancer
Targets：Wnt|β-catenin
Related Screening Libraries:Bioactive Compound Library Plus;Stem Cell Signaling Compound Library;Wnt/Hedgehog/Notch Compound Library;Anti-Cancer Compound Library;Anti-Aging Compound Library;Differentiation Inducing Compound Library;Cytoskeleton Compound Library;Neuroprotective Compound Library;Anti-Breast Cancer Compound Library;Transcription Factor-Targeted Library;Anti-Liver Cancer Compound Library ;Anti-Colorectal Cancer Compound Library ;Anti-Prostate Cancer Compound Library;Anti-Pulmonary Fibrosis Compound Library;Cancer Stem Cells Compound Library;
Related Small Molecules:Wnt/β-catenin agonist 1;ARUK3001185;Gallocyanine chloride;Fz7-21;NRX-252114;Foxy-5 TFA;Wnt/β-catenin agonist 4;JW74;IQ 1;Heparan Sulfate;CDK8-IN-11 hydrochloride;ETC-159;(E)-Ferulic acid-d3;Laduviglusib (GMP);NRX-252262;Toxoflavin;KY-05009;HLY78;Wnt-C59;Wogonin;NCB-0846;KY-02327;CCT031374 hydrobromide;β-catenin-IN-4;Echinacoside;JW67;IWP-4;Triptonide;Prodigiosin
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