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Darovasertib
CAS No. : 1874276-76-2
Biological Activity:Darovasertib (LXS196) is a potent, selective and orally active protein kinase C (PKC) inhibitor, with IC50 values of 1.9 nM, 0.4 nM and 3.1 μM for PKCα, PKCθ and GSK3β, respectively. Darovasertib has the potential for uveal melanoma research[2].
Research Area:Cancer
Targets:PKC
Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Epigenetics Compound Library;Kinase Inhibitor Library;TGF-beta/Smad Compound Library;Anti-Cancer Compound Library;Clinical Compound Library;Drug Repurposing Compound Library;Reprogramming Compound Library;Oxygen Sensing Compound Library;Cytoskeleton Compound Library;Orally Active Compound Library;Cancer Stem Cells Compound Library;Coagulation and Anti-coagulation Compound Library;
Related Small Molecules:[Ala107]MBP(104-118) TFA;BJE6-106;Myelin Basic Protein;Staurosporine;PKC-iota inhibitor 1;Hypericin;Malantide;PKCiota-IN-2 formic;PF-4950834;C8 Dihydroceramide;SC-9;DL-erythro-Dihydrosphingosine;Safingol;ZIP;Psychosine-d5;TPPB;Enzastaurin;Protein Kinase C (19-31);Protein kinase inhibitor H-7 dihydrochloride;Teleocidin A1;Ro 31-8220;[Ser25] Protein Kinase C (19-31);CGP60474
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