CYP3cide

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CYP3cide

CAS No. : 1390637-82-7

Biological Activity:CYP3cide (PF-4981517) is a potent, selective and time-dependent inhibitor of cytochrome P4503A4 (CYP3A4). The IC50 values for Midazolam 1’-hydroxylase activity are 0.03 μM, 17 μM, and 71 μM for CYP3A4, CYP3A5, and CYP3A7, respectively. CYP3cide can be used to distinguish the contributions of CYP3A4 versus CYP3A5 on drug metabolism.

Research Area:Others

Targets:Cytochrome P450

Related Small Molecules:SR9186;AMG-208;CYP1B1-IN-1;CYP2C9/CYP2C19-IN-1;Hypericin;Galeterone;Ranitidine;Bergapten;Ginsenoside Rd;AS1810722;Isoglycycoumarin;Polygalaxanthone III;Phenyltoloxamine;Ezutromid;Seviteronel;β-​Apo-​8′-​carotenal;Diosmetin-d3;EDP-305;Fipronil;Cholesterol 24-hydroxylase-IN-1;TMS;Harmalol hydrochloride;Olivetol

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