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Curcumenol
CAS No. : 19431-84-6
Biological Activity：Curcumenol ((+)-Curcumenol) is a potent CYP3A4 inhibitor with an IC50 of 12.6 μM, which is one of constituents in the plants of medicinally important genus of Curcuma zedoaria, with neuroprotection, anti-inflammatory, anti-tumor and hepatoprotective activities. Curcumenol ((+)-Curcumenol) suppresses Akt-mediated NF-κB activation and p38 MAPK signaling pathway in LPS-stimulated BV-2 microglial cells[2].
Research Area：Cancer|Inflammation/Immunology|Neurological Disease
Targets：Cytochrome P450
Related Screening Libraries:Covalent Screening Library Plus;Natural Product Library Plus;Bioactive Compound Library Plus; Immunology/Inflammation Compound Library;Metabolism/Protease Compound Library;NF-κB Signaling Compound Library;Natural Product Library;Anti-Cancer Compound Library;Anti-Aging Compound Library;Covalent Screening Library;Antioxidant Compound Library;Oxygen Sensing Compound Library;Medicine Food Homology Compound Library;Terpenoids Library;Traditional Chinese Medicine Active Compound Library;Neuroprotective Compound Library;Food-Sourced Compound Library ;Targeted Diversity Library;Anti-Cancer Natural Product Library;Anti-inflammatory Traditional Chinese Medicine Active Compound Library;Plant-Sourced Natural Product Library;Human Metabolite Library;
Related Small Molecules:SR9186;AMG-208;CYP1B1-IN-1;CYP2C9/CYP2C19-IN-1;Hypericin;Galeterone;Ranitidine;Bergapten;Ginsenoside Rd;AS1810722;Isoglycycoumarin;Polygalaxanthone III;Phenyltoloxamine;Ezutromid;Seviteronel;β-Apo-8′-carotenal;Diosmetin-d3;EDP-305;Fipronil;Cholesterol 24-hydroxylase-IN-1;TMS;Harmalol hydrochloride;Olivetol
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