CU-T12-9

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CU-T12-9

CAS No. : 1821387-73-8

Biological Activity:CU-T12-9 is a specific TLR1/2 agonist with EC50 of 52.9 nM in HEK-Blue hTLR2 SEAP assay. CU-T12-9 activates both the innate and the adaptive immune systems. CU-T12-9 selectively activates the TLR1/2 heterodimer, not TLR2/6. CU-T12-9 signals through NF-κB and invokes an elevation of the downstream effectors TNF-α, IL-10, and iNOS.

Research Area:Cancer|Inflammation/Immunology

Targets:Toll-like Receptor (TLR)

Related Screening Libraries:Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;NF-κB Signaling Compound Library;Anti-Cancer Compound Library;Small Molecule Immuno-Oncology Compound Library;Antioxidant Compound Library;Reprogramming Compound Library;Oxygen Sensing Compound Library;Pyroptosis Compound Library;Anti-Pulmonary Fibrosis Compound Library;Cancer Stem Cells Compound Library;

Related Small Molecules:C29;TMX-201;RS 09;ODN 20844;TLR7/8-IN-1;TLR8 agonist 5;Sulfo-ara-F-NMN;TLR7/8 antagonist 1;Gardiquimod;PF-4878691;Tri(TLR4-IN-C34-PEG2-amide-PEG1)-amide-C3-COOH;Pepinh-TRIF TFA;Afimetoran;Schaftoside;ODN 2088;CU-CPT22;UC-1V150;Diprovocim-X;CL264;MMG-11 quarterhydrate;CU-CPT 4a;TLR7/8 agonist 4;SM-324405;Enpatoran

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