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Convallatoxin
CAS No. : 508-75-8
Biological Activity：Convallatoxin is a cardiac glycoside isolated from Adonis amurensis Regel et Radde. Convallatoxin ameliorates colitic inflammation via activation of PPARγ and suppression of NF-κB. Convallatoxin is a P-glycoprotein (P-gp) substrate and recognized Val982 as an important amino acid involved in its transport. Convallatoxin is an enhancer of ligand-induced MOR endocytosis with high potency and efficacy. Anti-inflammatory and anti-proliferative properties[2][3].
Research Area：Cancer|Inflammation/Immunology
Targets：NF-κB|PPAR|P-glycoprotein
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