Compound E

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Compound E

CAS No. : 209986-17-4

Biological Activity:Compound E is a γ-secretase inhibitor. Compound E bloks β-amyloid(40), β-amyloid(42), and Notch γ-secretase cleavage with IC50s of 0.24, 0.37, 0.32 nM, respectively.

Research Area:Cancer

Targets:γ-secretase

Related Screening Libraries:Bioactive Compound Library Plus;

Related Small Molecules:γ-Secretase modulator 4;ELN318463;Crenigacestat;Aβ42-IN-1 free base;Fosciclopirox;JNJ-40418677;gamma-secretase modulator 3;γ-Secretase modulator 11 hydrochloride;γ-Secretase modulator 12;Aβ42-IN-2;DAPT (GMP);BPN-15606;LY-411575 (isomer 3);BMS 433796;YO-01027 (GMP);BI-1408;Nirogacestat dihydrobromide;gamma-secretase modulator 1 hydrochloride;MRK-560;Semagacestat;Begacestat;GSM-1;L-685458

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