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CMLD012073
CAS No. : 2368900-32-5
Biological Activity：CMLD012073 is an amidino-rocaglates and is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor. CMLD012073 inhibits the growth of NIH/3T3 cells with an IC50 of 10 nM. CMLD012073 inhibits eukaryotic translation initiation by modifying the behavior of the RNA helicase (eIF4A).
Research Area：Cancer
Targets：Eukaryotic Initiation Factor (eIF)
Related Small Molecules:4E2RCat;CMLD012612;Rocaglamide;CMLD012072;eIF4A3-IN-6;4EGI-1;GCN2-IN-1;eIF4A3-IN-1;ML291;EIF2α activator 2;eIF4A3-IN-5;2BAct;rel-Zotatifin;eIF4A3-IN-8;eIF4E-IN-2;eIF4A3-IN-2;ATPγS tetralithium salt;eIF4A3-IN-4;GCN2-IN-6;Episilvestrol;CR-1-31-B;Rohinitib;eIF4E-IN-1;GCN2iB
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