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Cenisertib
CAS No. : 871357-89-0
Biological Activity：Cenisertib (AS-703569) is an ATP-competitive multi-kinase inhibitor that blocks the activity of Aurora-kinase-A/B, ABL1, AKT, STAT5 and FLT3. Cenisertib induces major growth-inhibitory effects by blocking the activity of several different molecular targets in neoplastic mast cells (MC). Cenisertib inhibits tumor growth in xenograft models of pancreatic, breast, colon, ovarian, and lung tumors and leukemia[2][3].
Research Area：Cancer
Targets：Akt|FLT3|STAT|Bcr-Abl|Aurora Kinase
Related Screening Libraries:Clinical Compound Library Plus;Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;Epigenetics Compound Library;Immunology/Inflammation Compound Library;JAK/STAT Compound Library;Kinase Inhibitor Library;PI3K/Akt/mTOR Compound Library;Protein Tyrosine Kinase Compound Library;Stem Cell Signaling Compound Library;Anti-Cancer Compound Library;Clinical Compound Library;Autophagy Compound Library;Anti-Aging Compound Library;Differentiation Inducing Compound Library;Oxygen Sensing Compound Library;Glycolysis Compound Library;Cytoskeleton Compound Library;Glutamine Metabolism Compound Library;Anti-Alzheimer’s Disease Compound Library;Anti-Breast Cancer Compound Library;Anti-Lung Cancer Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Blood Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Anti-Parkinson’s Disease Compound Library;Neurodegenerative Disease-related Compound Library;Anti-Obesity Compound Library;Angiogenesis-Related Compound Library;Transcription Factor-Targeted Library;Glucose Metabolism Compound Library;Anti-Liver Cancer Compound Library ;Anti-Colorectal Cancer Compound Library ;Anti-Prostate Cancer Compound Library;Anti-Pulmonary Fibrosis Compound Library;Cancer Stem Cells Compound Library;
Related Small Molecules:Akt/NF-κB/JNK-IN-1;DB0614;Cirsilineol;Ochromycinone;AT9283;C188-9;Bafetinib;Cyclovirobuxine D;STAT3-IN-10;(E/Z)-Zotiraciclib;Pivanex;AKTide-2T;C188;Crotonoside;Sennidin A;SNIPER(ABL)-039;Flumatinib mesylate;IHMT-TRK-284;Niclosamide monohydrate;FLT3-IN-13;PDGFRα/FLT3-ITD-IN-2;MS98;FLT3/CDK4-IN-1;PP2A Cancerous-IN-1;STAT3-IN-1;STAT3 degrader-1;1,3-Dicaffeoylquinic acid;Chiauranib
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