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CBR-470-1
CAS No. : 2416095-06-0
Biological Activity：CBR-470-1 is an inhibitor of the glycolytic enzyme phosphoglycerate kinase 1 (PGK1). CBR-470-1 is also a non-covalent Nrf2 activator. CBR-470-1 protects SH-SY5Y neuronal cells against MPP+-induced cytotoxicity through activation of the Keap1-Nrf2 cascade[2].
Research Area：Metabolic Disease|Neurological Disease
Targets：Keap1-Nrf2
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Related Small Molecules:Mangiferin;Antioxidant agent-5;Curcumin;Antroquinonol;Resveratrol;NXPZ-2;Eriodictyol;ML334;S-Allylmercaptocysteine;NK-252;Ginsenoside Rh3;4-Hydroxyphenylacetic acid-d6;Kinsenoside;Pyridoxine-d3 hydrochloride;Pyridoxine;Carnosol;Corynoline;5,7-Dihydroxychromone;Carlinoside;Pyridoxine-d2 hydrochloride;Pyridoxine-13C4 hydrochloride;4-Hydroxyphenylacetic acid;Poricoic acid A;Hinokitiol;Nrf2-ARE/hMAO-B/QR2 modulator 1;CBR-470-2;Danshensu
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