For research use only. We do not sell to patients.

CA77.1

CAS No. : 2412270-22-3

Biological Activity：CA77.1 is a potent, brain-penetrant and orally active chaperone-mediated autophagy (CMA) activator with favorable pharmacokinetics. CA77.1 is a derivative of AR7 (HY-101106) and can increase the expression of the lysosomal receptor LAMP2A in lysosomes. CA77.1 improves behavior and neuropathology in PS19 mice model and can be used for alzheimer’s disease research.

Research Area：Neurological Disease

Targets：Autophagy

Related Screening Libraries:Bioactive Compound Library Plus;Autophagy Compound Library;Anti-Alzheimer’s Disease Compound Library;Neurodegenerative Disease-related Compound Library;Targeted Diversity Library;

Related Small Molecules:Physalin A;Stauprimide;Pregnenolone monosulfate sodium;Notoginsenoside Fc;AGN 193109-d7;AT9283;Ciclopirox-d11;BIX-01294;Wogonoside;Cyclovirobuxine D;Clotrimazole-d5;Curcumin;Loperamide-d6 N-Oxide;Physalin B;Colistin sulfate;Salvianolic acid B;10074-G5;Dehydrocorydaline;Glucosamine-13C hydrochloride

About Us:

MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use；
Structurally and synthetically diverse biologically active compounds；
roduct quality is the key to our success and we take pride in offering only the highest-grade products.；
We provide HNMR, LC-MS, HPLC, stability testing and activity assays of our products to clients.；
Product identity, quality, purity and activity are assured by our robust quality control programs and procedures.；

Structurally and synthetically diverse biologically active compounds；

Customized order volume ranging from milligrams to kilograms scale；

We provide customer-oriented services. To explore more, please contact us at [email protected]. Our team will gladly assist you.

Top Publications Citing Use of MCE Products