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Brequinar
CAS No. : 96187-53-0
Biological Activity:Brequinar (DUP785) is a potent inhibitor of dihydroorotate dehydrogenase (DHODH) with an IC50 of 5.2 nM for human DHODH. Brequinar has potent activities against a broad spectrum of viruses. Brequinar also has an anti-SARS2 activity.
Research Area:Cancer|Infection|Inflammation/Immunology
Targets:Dihydroorotate Dehydrogenase|DNA/RNA Synthesis|Virus Protease|SARS-CoV
Related Screening Libraries:Drug Repurposing Compound Library Plus; Clinical Compound Library Plus;Bioactive Compound Library Plus;Anti-Infection Compound Library;Cell Cycle/DNA Damage Compound Library;Immunology/Inflammation Compound Library;Metabolism/Protease Compound Library;Anti-Cancer Compound Library;Clinical Compound Library;Antiviral Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Ferroptosis Compound Library;FDA Approved & Pharmacopeial Drug Library;Mitochondria-Targeted Compound Library;Human Metabolite Library;
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