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BMS 777607
CAS No. : 1025720-94-8
Biological Activity：BMS 777607 (BMS 817378) is a Met-related inhibitor for c-Met, Axl, Ron and Tyro3 with IC50s of 3.9 nM, 1.1 nM, 1.8 nM and 4.3 nM, respectively, and 40-fold more selective for Met-related targets than Lck, VEGFR-2, and TrkA/B, with more than 500-fold greater selectivity versus all other receptor and non receptor kinases.
Research Area：Cancer
Targets：c-Met/HGFR|TAM Receptor
Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Kinase Inhibitor Library;Protein Tyrosine Kinase Compound Library;Anti-Cancer Compound Library;Clinical Compound Library;Drug Repurposing Compound Library;Anti-COVID-19 Compound Library;Anti-Lung Cancer Compound Library;Angiogenesis-Related Compound Library;Anti-Liver Cancer Compound Library ;Anti-Colorectal Cancer Compound Library ;Cancer Stem Cells Compound Library;
Related Small Molecules:AMG-208;D6808;MET kinase-IN-2;c-Met-IN-9;Tyrosine kinase-IN-4;Axl-IN-5;PROTAC Axl Degrader 2;Savolitinib;UNC2250;Foretinib;PF-04217903 phenolsulfonate;MK-2461;R916562;XL092;SAR125844;MK-8033 hydrochloride;Axl-IN-3;Gilteritinib-d8;BPI-9016M;Ficlatuzumab;UNC1062;Bemcentinib;Meleagrin;Axl-IN-6;c-Met inhibitor 1;ONO-7475;Pamufetinib;PHA-665752
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