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BMS-688521
CAS No. : 893397-44-9
Biological Activity:BMS-688521 is a highly potent, orally active inhibitor of the LFA-1/ICAM interaction, with an IC50 of 2.5 nM in the adhesion assay and an IC50 of 60 nM in the MLR assay. BMS-688521 is efficacious in a mouse allergic eosinophilic lung inflammation model.
Research Area:Inflammation/Immunology
Targets:Integrin
Related Screening Libraries:Bioactive Compound Library Plus;
Related Small Molecules:GRGDSPK;Integrin Binding Peptide;Cyclo(Arg-Gly-Asp-D-Phe-Cys);Zaurategrast ethyl ester sulfate;HSDVHK-NH2;Lifitegrast sodium;TC-I 15;α2β1 Integrin Ligand Peptide;Integrin modulator 1;Veltuzumab;GRGDSP TFA;Cyclo(-RGDfK) TFA;Zalunfiban;K34c;THI0019;RGD;Arg-Gly-Asp-Ser (TFA);BIRT 377;αvβ1 integrin-IN-1;RGD-4C;LXW7;Fradafiban;Firategrast;EILEVPST;Valategrast hydrochloride
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