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BMS-1166-N-piperidine-CO-N-piperazine
CAS No. : 2447066-14-8
Biological Activity：BMS-1166-N-piperidine-CO-N-piperazine incorporates a ligand for PD-1/PD-L1 immune checkpoint, and a PROTAC linker. BMS-1166-N-piperidine-CO-N-piperazine can be used in the synthesis of PROTAC PD-1/PD-L1 degrader-1 (HY-131183). PROTAC PD-1/PD-L1 degrader-1 inhibits PD-1/PD-L1 interaction with an IC50 of 39.2 nM.
Research Area：Cancer
Targets：Target Protein Ligand-Linker Conjugates
Related Small Molecules:K-Ras ligand-Linker Conjugate 3;K-Ras ligand-Linker Conjugate 1;MRTX849 ethoxypropanoic acid;K-Ras ligand-Linker Conjugate 6;BRD4 ligand-Linker Conjugate 1;Ahx-DM1 TFA;K-Ras ligand-Linker Conjugate 2;K-Ras ligand-Linker Conjugate 5;Desmorpholinyl Quizartinib-PEG2-COOH;K-Ras ligand-Linker Conjugate 4;(Rac)-PROTAC PARP/EGFR ligand 1;ERRα Ligand-Linker Conjugates 1;FAK ligand-Linker Conjugate 1
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
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