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BIO5192

CAS No. : 327613-57-0

Biological Activity：BIO5192 is a selective and potent integrin α4β1 (VLA-4) inhibitor (K_d<10 pM). BIO5192 selectively binds to α4β1 (IC₅₀=1.8 nM) over a range of other integrins. BIO5192 results in a 30-fold increase in mobilization of murine hematopoietic stem and progenitors (HSPCs) over basal levels^[2].

Research Area：Inflammation/Immunology

Targets：Integrin

Related Screening Libraries:Covalent Screening Library Plus;Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Covalent Screening Library;Cytoskeleton Compound Library;

Related Small Molecules:GRGDSPK;Integrin Binding Peptide;Cyclo(Arg-Gly-Asp-D-Phe-Cys);Zaurategrast ethyl ester sulfate;HSDVHK-NH2;Lifitegrast sodium;TC-I 15;α2β1 Integrin Ligand Peptide;Integrin modulator 1;Veltuzumab;GRGDSP TFA;Cyclo(-RGDfK) TFA;Zalunfiban;K34c;THI0019;RGD;Arg-Gly-Asp-Ser (TFA);BIRT 377;αvβ1 integrin-IN-1;RGD-4C;LXW7;Fradafiban;Firategrast;EILEVPST;Valategrast hydrochloride

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