For research use only. We do not sell to patients.
BI 653048 phosphate
CAS No. : 1198784-97-2
Biological Activity：BI 653048 phosphate is a selective and orally active nonsteroidal glucocorticoid (GC) agonist with an IC50 value of 55 nM. BI 653048 phosphate inhibits CP1A2, CYP2D6, CYP2C9, CYP2C19 and CYP3A4 isoforms’ activity and reduces affinity for the hERG ion channel (IC50>30 μM)[2]. BI 653048 phosphate is extracted from patent WO2005028501A1 (Compound 103), is also a HCV NS3 protease inhibitor that can reduce viral loads infected with the hepatitis C virus[3].
Research Area：Infection|Inflammation/Immunology
Targets：Glucocorticoid Receptor|HCV Protease|Cytochrome P450
Related Small Molecules:SR9186;AMG-208;Deflazacort-D5;NS5A-IN-1;CYP1B1-IN-1;CYP2C9/CYP2C19-IN-1;Hypericin;Grazoprevir potassium salt;BMS-986144;Galeterone;Ranitidine;Bergapten;Ginsenoside Rd;AS1810722;Isoglycycoumarin
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
About Us:
- MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use；
- Structurally and synthetically diverse biologically active compounds；
- roduct quality is the key to our success and we take pride in offering only the highest-grade products.；
- We provide HNMR, LC-MS, HPLC, stability testing and activity assays of our products to clients.；
- Product identity, quality, purity and activity are assured by our robust quality control programs and procedures.；
- Customized order volume ranging from milligrams to kilograms scale；
Structurally and synthetically diverse biologically active compounds；
We provide customer-oriented services. To explore more, please contact us at [email protected]. Our team will gladly assist you.
