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Bexarotene
CAS No. : 153559-49-0
Biological Activity：Bexarotene (LGD1069) is a high-affinity and selective retinoid X receptors (RXR) agonist with EC50s of 33, 24, 25 nM for RXRα, RXRβ, and RXRγ, respectively. Bexarotene shows limited affinity for RAR receptors (EC50 >10000 nM)[2][3]. Bexarotene can be used for the research of cutaneous T-cell lymphoma.
Research Area：Cancer
Targets：Autophagy|RAR/RXR
Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Metabolism/Protease Compound Library;FDA-Approved Drug Library;Anti-Cancer Compound Library;Antiviral Compound Library;Autophagy Compound Library;Drug Repurposing Compound Library;Differentiation Inducing Compound Library;Reprogramming Compound Library;Anti-COVID-19 Compound Library;Orally Active Compound Library;FDA Approved & Pharmacopeial Drug Library;Drug-Induced Liver Injury (DILI) Compound Library;Anti-Blood Cancer Compound Library;Targeted Therapy Drug Library ;Transcription Factor-Targeted Library;Rare Diseases Drug Library;EMA-Approved Drug Library;FDA-Approved Anticancer Drug Library;Human Metabolite Library;Nuclear Receptor Compound Library;
Related Small Molecules:AGN 193109-d7;Retinoic acid;AC-261066;Magnolol;ER 50891;(+)-Talarozole;Trifarotene;β-Apo-13-carotenone;Bigelovin;CD2665;BMS453;9-cis-Retinoic acid;AGN-195183;Fenretinide;Liarozole dihydrochloride;BMS-195614;LE135;Tamibarotene;UVI 3003;PROTAC RAR Degrader-1;BMS641;Tarenflurbil
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