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Benzamil

CAS No. : 2898-76-2

Biological Activity：Benzamil (Benzylamiloride), an Amiloride analogue, is a Na⁺/Ca²⁺ exchanger (NCX) inhibitor (IC₅₀~100 nM). Benzamil also is a non-selective Deg/epithelial sodium channels (ENaC) blocker, and can potentiate myogenic vasoconstriction. Benzamil inhibits TRPP3-mediated Ca²⁺-activated currents, with an IC₅₀ of 1.1 μM^[2][3].

Research Area：Neurological Disease

Targets：Sodium Channel|Na+/Ca2+ Exchanger

Related Small Molecules:Lu AE98134;Zandatrigine;SN 6;Veratridine;Brompheniramine-d6 maleate;GX-674;Dibucaine;Sodium Channel inhibitor 2;3-Deoxyaconitine;20(S)-Ginsenoside Rg3;Tocainide hydrochloride;Licarbazepine-d4-1;Metaflumizone-d4;β-Pompilidotoxin;Nav1.1 activator 1;ICA-121431;Brompheniramine maleate;ABBV-318;PF 05089771;DPI 201-106;TC-N 1752

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